Proteomics

Dataset Information

0

Adult mouse choroid plexus OTX2 Co-IP


ABSTRACT: To analyze OTX2 function in adult choroid plexus, we performed several OTX2 co-immunoprecipitation (co-IP) experiments with mass spectrometry analysis to identify potential protein partners. We previously discovered that OTX2 protein also accumulates non-cell autonomously in subventricular zone (SVZ) and rostral migratory stream (RMS) astrocytes and in visual cortex (VCx) parvalbumin cells. The identification of alternate protein partners in cell-autonomous and non-cell-autonomous contexts would suggest OTX2 takes on specific roles after transferring between cells. In order to test this hypothesis, and to reinforce choroid plexus analysis, we also performed OTX2 co-IP on lysates from adult mouse SVZ, RMS and VCx.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Rostral Migratory Stream, Visual Cortex, Choroid Plexus, Subventricular Zone

SUBMITTER: Valentin SABATET  

LAB HEAD: Damarys Loew

PROVIDER: PXD021244 | Pride | 2021-08-23

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
C0723FD.raw Raw
C0724FD.raw Raw
C0725FD.raw Raw
C0726FD.raw Raw
C0727FD.raw Raw
Items per page:
1 - 5 of 74

Similar Datasets

2021-08-31 | GSE157386 | GEO
| PRJNA661094 | ENA
2009-02-01 | E-GEOD-14098 | biostudies-arrayexpress
2013-02-05 | E-GEOD-27630 | biostudies-arrayexpress
2019-05-01 | GSE126327 | GEO
2012-08-01 | E-GEOD-29733 | biostudies-arrayexpress
2024-09-27 | GSE264154 | GEO
2022-12-15 | GSE218188 | GEO
| PRJNA138529 | ENA
2024-05-06 | GSE246851 | GEO