Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Stem Cell, Cell Culture, Fibroblast
DISEASE(S): Breast Cancer
SUBMITTER: Amir Prior
LAB HEAD: Adit Ben-Baruch
PROVIDER: PXD022635 | Pride | 2021-08-10
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
FS1_6753_ABBA_2A_1_090518.raw | Raw | |||
FS1_6753_ABBA_2B_1_090518.raw | Raw | |||
FS1_6753_ABBA_3A_1_090518.raw | Raw | |||
FS1_6753_ABBA_3B_1_090518.raw | Raw | |||
FS1_6753_ABBA_4A_1_090518.raw | Raw |
Items per page: 5 1 - 5 of 11 |
Rubinstein-Achiasaf Linor L Morein Dina D Ben-Yaakov Hagar H Liubomirski Yulia Y Meshel Tsipi T Elbaz Eti E Dorot Orly O Pichinuk Edward E Gershovits Michael M Weil Miguel M Ben-Baruch Adit A
Cancers 20210323 6
The pro-inflammatory cytokines tumor necrosis factor α (TNFα) and interleukin 1β (IL-1β) are expressed simultaneously and have tumor-promoting roles in breast cancer. In parallel, mesenchymal stem cells (MSCs) undergo conversion at the tumor site to cancer-associated fibroblasts (CAFs), which are generally connected to enhanced tumor progression. Here, we determined the impact of consistent inflammatory stimulation on stromal cell plasticity. MSCs that were persistently stimulated by TNFα + IL-1 ...[more]