Analysis of the protein cargo of extracellular vesicles isolated from cultured line H9 human stem cells
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ABSTRACT: Extracellular vesicles (EV) are secreted by nearly every mammalian cell type and contain a wealth of bioactive cargo capable of modulating target cell physiology and function though a variety of paracrine signaling mechanisms (Leavitt et al., 2019). Human embryonic stem cell (hESC)-derived extracellular vesicles (hESC-derived EV), were extracted from the hESC line H9 (WA09 Wicell Research Institute, Inc., Madison, WI). We analyzed the bioactive protein cargo to identify components that help to resolve radiation-induced injury to the lung in mice when injected in vivo.
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Embryonic Stem Cell
SUBMITTER: Charles Limoli
LAB HEAD: Charles Limoli
PROVIDER: PXD023213 | Pride | 2021-02-24
REPOSITORIES: Pride
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