Dataset Information

Human TRPV4 LC-MS protein interactor screen

ABSTRACT: TRPV4 is a cell surface-expressed calcium-permeable cation channel that mediates cell-specific effects on cellular morphology and function. Dominant missense mutations of TRPV4 cause various forms of inherited neuropathy, but the pathogenic mechanisms are unknown. Using an unbiased screen, we sought to identify novel TRPV4 interactors that may be relevant to disease pathogenesis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Charcot-marie-tooth Disease Axonal Type 2c

SUBMITTER: Brett McCray

LAB HEAD: Charlotte Jane Sumner

PROVIDER: PXD023758 | Pride | 2021-01-29

REPOSITORIES: Pride

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Human TRPV4 LC-MS protein interactor screen

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