Proteomics

Dataset Information

0

Global ubiquitinome profiling identify Nedd4 as aregulator of Profilin 1 and actin remodeling in neural crest cells


ABSTRACT: We utilized quantitative analyses of the proteome, transcriptome, and ubiquitinome to study how ubiquitination and NEDD4 control neural crest cell survival and stem-cell-like properties. We report 276 novel NEDD4 targets in neural crest cells and show that loss of NEDD4 leads to a striking global reduction in specific ubiquitin lysine linkages.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Neural Crest

SUBMITTER: Oded Kleifeld  

LAB HEAD: Quenten Schwarz

PROVIDER: PXD024103 | Pride | 2022-02-08

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
OK20130809_PMSILACTotalS_P1.raw Raw
OK20130809_PMSILACTotalS_P2.raw Raw
OK20130809_PMSILACTotalS_P3.raw Raw
OK20130809_PMSILACTotalS_P4.raw Raw
OK20130809_PMSILACTotalS_P5.raw Raw
Items per page:
1 - 5 of 53

Similar Datasets

2021-02-05 | PXD022367 | Pride
2022-03-02 | GSE197631 | GEO
2023-11-13 | PXD038655 | Pride
2024-06-18 | PXD034527 | Pride
2011-10-26 | E-GEOD-19085 | biostudies-arrayexpress
2016-07-06 | PXD001214 | Pride
2016-12-07 | PXD005240 | Pride
2022-05-20 | PXD031703 | Pride
2023-10-24 | PXD035401 | Pride
2022-04-14 | PXD032085 | Pride