Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Preadipocyte, Adipose Tissue
SUBMITTER: Ivo Hendriks
LAB HEAD: Michael Lund Nielsen
PROVIDER: PXD024144 | Pride | 2022-02-18
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 99 |
Zhao Xu X Hendriks Ivo A IA Le Gras Stéphanie S Ye Tao T Ramos-Alonso Lucía L Nguéa P Aurélie A Lien Guro Flor GF Ghasemi Fatemeh F Klungland Arne A Jost Bernard B Enserink Jorrit M JM Nielsen Michael L ML Chymkowitch Pierre P
Nucleic acids research 20220201 3
Tight control of gene expression networks required for adipose tissue formation and plasticity is essential for adaptation to energy needs and environmental cues. However, the mechanisms that orchestrate the global and dramatic transcriptional changes leading to adipocyte differentiation remain to be fully unraveled. We investigated the regulation of nascent transcription by the sumoylation pathway during adipocyte differentiation using SLAMseq and ChIPseq. We discovered that the sumoylation pat ...[more]