Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Kidney
SUBMITTER: Mingyang Hu
LAB HEAD: Sijie Zhou
PROVIDER: PXD024543 | Pride | 2021-09-10
REPOSITORIES: Pride
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Hu Mingyang M Fang Jiuyuan J Wang Huijuan H Zhou Sijie S
Frontiers in genetics 20210407
Diabetic nephropathy is the most common chronic kidney disease in the world and the main cause of end-stage renal disease (ESRD). The structural integrity of podocytes is fundamental to the normal function of the glomerulus, and the role of glycogen synthase kinase 3β (GSK-3β) in podocytes is complicated. A thorough understanding of GSK-3β is crucial to understand the mechanism of diabetic nephropathy. To analyze the roles of GSK-3β in podocytes, GSK-3β knockdown lentivirus by clustered regularl ...[more]