Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Heart
SUBMITTER: Xiaohong Wei
LAB HEAD: Jingyan Han
PROVIDER: PXD024641 | Pride | 2021-07-26
REPOSITORIES: Pride
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Frontiers in physiology 20210628
<h4>Background</h4>T<sub>89</sub>, a traditional Chinese medicine, has passed phase II, and is undergoing phase III clinical trials for treatment of ischemic cardiovascular disease by the US FDA. However, the role of T<sub>89</sub> on isoproterenol (ISO)-induced cardiac injury is unknown. The present study aimed to explore the effect and underlying mechanism of T<sub>89</sub> on ISO-induced cardiac injury.<h4>Methods</h4>Male Sprague-Dawley rats received subcutaneous injection of ISO saline solu ...[more]