Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: Duc Duong
LAB HEAD: Chadwick Hales, MD, PhD
PROVIDER: PXD024724 | Pride | 2021-09-10
REPOSITORIES: Pride
Action | DRS | |||
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HUMAN_ABETA4ISO.fasta | Fasta | |||
checksum.txt | Txt | |||
cxhales_b3_tmt_.pdResult | Other | |||
cxhales_b3_tmt_01.raw | Raw | |||
cxhales_b3_tmt_02.raw | Raw |
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Molecular neurodegeneration 20210625 1
<h4>Background</h4>There is an association between repetitive head injury (RHI) and a pathologic diagnosis of chronic traumatic encephalopathy (CTE) characterized by the aggregation of proteins including tau. The underlying molecular events that cause these abnormal protein accumulations remain unclear. Here, we hypothesized that identifying the human brain proteome from serial CTE stages (CTE I-IV) would provide critical new insights into CTE pathogenesis. Brain samples from frontotemporal loba ...[more]