Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: Ricard Rodriguez-Mias
LAB HEAD: Judit Villen
PROVIDER: PXD024939 | Pride | 2023-05-10
REPOSITORIES: Pride
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Vera-Montecinos América A Rodríguez-Mias Ricard R Vila Èlia È Villén Judit J Ramos Belén B
Frontiers in pharmacology 20230323
The dorsolateral prefrontal cortex (DLPFC) has a crucial role in cognitive functioning and negative symptoms in schizophrenia. However, limited information of altered protein networks is available in this region in schizophrenia. We performed a proteomic analysis using single-shot liquid chromatography-tandem mass spectrometry of grey matter of postmortem DLPFC in chronic schizophrenia subjects (n = 20) and unaffected subjects (n = 20) followed by bioinformatic analysis to identify altered prote ...[more]