Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Testis
SUBMITTER: Alfonso Bolado
LAB HEAD: Alexander von Kriegsheim
PROVIDER: PXD025409 | Pride | 2021-11-03
REPOSITORIES: Pride
Action | DRS | |||
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L_CG17669_1.raw | Raw | |||
L_CG17669_2.raw | Raw | |||
L_CG17669_3.raw | Raw | |||
L_CG17669_4.raw | Raw | |||
L_CG6980_1.raw | Raw |
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Biology open 20211028 10
Ciliary motility is powered by a suite of highly conserved axoneme-specific dynein motor complexes. In humans, the impairment of these motors through mutation results in the disease primary ciliary dyskinesia (PCD). Studies in Drosophila have helped to validate several PCD genes whose products are required for cytoplasmic pre-assembly of axonemal dynein motors. Here we report the characterisation of the Drosophila orthologue of the less-known assembly factor DNAAF3. This gene, CG17669 (Dnaaf3), ...[more]