Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Equus Caballus (horse)
TISSUE(S): Articular Cartilage, Bone, Synovial Tissue
SUBMITTER: Louise Bundgaard
LAB HEAD: Louise Bundgaard
PROVIDER: PXD025882 | Pride | 2022-10-12
REPOSITORIES: pride
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20181105_FJ_LB_CAR4.raw | Raw | |||
20181105_FJ_LB_CAR6.raw | Raw | |||
20181105_FJ_LB_SB7.raw | Raw | |||
20181105_FJ_LB_SB8.raw | Raw | |||
20181105_FJ_LB_SB9.raw | Raw |
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Bundgaard L L Åhrman E E Malmström J J Auf dem Keller U U Walters M M Jacobsen S S
Osteoarthritis and cartilage 20210920 1
<h4>Objective</h4>The objectives of this study was to establish a sensitive and reproducible method to map the cartilage and subchondral bone proteomes in quantitative terms, and mine the proteomes for proteins of particular interest in the pathogenesis of osteoarthritis (OA). The horse was used as a model animal.<h4>Design</h4>Protein was extracted from articular cartilage and subchondral bone samples from three horses in triplicate by pressure cycling technology or ultrasonication. Digested pr ...[more]