Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell
DISEASE(S): Disease Free
SUBMITTER: Jingyun Lee
LAB HEAD: Cristina M. Furdui
PROVIDER: PXD025896 | Pride | 2022-02-17
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Abl2N_phos_01_TiO2.msf | Msf | |||
Abl2N_phos_01_TiO2.mzML | Mzml | |||
Abl2N_phos_01_TiO2.mzid.gz | Mzid | |||
Abl2N_phos_01_TiO2.raw | Raw | |||
Abl2N_phos_02_TiO2.msf | Msf |
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The Journal of biological chemistry 20210616 1
Abl family kinases are nonreceptor tyrosine kinases activated by diverse cellular stimuli that regulate cytoskeleton organization, morphogenesis, and adhesion. The catalytic activity of Abl family kinases is tightly regulated in cells by a complex set of intramolecular and intermolecular interactions and post-translational modifications. For example, the platelet-derived growth factor receptor beta (PDGFRβ), important for cell proliferation and chemotaxis, is a potent activator of Abl family kin ...[more]