Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Lung
SUBMITTER: Daniel Veyel
LAB HEAD: Wolfgang Rist
PROVIDER: PXD026222 | Pride | 2024-09-10
REPOSITORIES: pride
Items per page: 5 1 - 5 of 27 |
Klee Stephan S Picart-Armada Sergio S Wenger Kathrin K Birk Gerald G Quast Karsten K Veyel Daniel D Rist Wolfgang W Violet Coralie C Luippold Andreas A Haslinger Christian C Thomas Matthew M Fernandez-Albert Francesc F Kästle Marc M
American journal of physiology. Lung cellular and molecular physiology 20230110 3
The most common preclinical, in vivo model to study lung fibrosis is the bleomycin-induced lung fibrosis model in 2- to 3-mo-old mice. Although this model resembles key aspects of idiopathic pulmonary fibrosis (IPF), there are limitations in its predictability for the human disease. One of the main differences is the juvenile age of animals that are commonly used in experiments, resembling humans of around 20 yr. Because IPF patients are usually older than 60 yr, aging appears to play an importa ...[more]