Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Trypanosoma Brucei
TISSUE(S): Cell Suspension Culture
SUBMITTER: Arthur Gunzl
LAB HEAD: Arthur Gunzl
PROVIDER: PXD026239 | Pride | 2021-12-15
REPOSITORIES: Pride
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EOT15-2543_SHPark_r_42663_9.raw | Raw | |||
EOT15-2544_SHPark_r_42663_8.raw | Raw | |||
EOT15-2545_SHPark_r_42663_7.raw | Raw | |||
EOT15-2546_SHPark_r_42663_2.raw | Raw | |||
EOT15-2547_SHPark_r_42663_1.raw | Raw |
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Srivastava Ankita A Ambrósio Daniela L DL Tasak Monika M Gosavi Ujwala U Günzl Arthur A
Nucleic acids research 20211201 22
The pre-mRNA splicing factor PRP19 is recruited into the spliceosome after forming the PRP19/CDC5L complex in humans and the Nineteen complex in yeast. Additionally, 'PRP19-related' proteins enter the spliceosome individually or in pre-assemblies that differ in these systems. The protistan family Trypanosomatidae, which harbors parasites such as Trypanosoma brucei, diverged early during evolution from opisthokonts. While introns are rare in these organisms, spliced leader trans splicing is an ob ...[more]