The trade-off hypothesis of oocyte quantity and quality in gonadotropin-stimulated ovarian regime: proteome profile of superovulated vs naturally ovulated mouse oocytes
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ABSTRACT: In order to clarify if there is a tradeoff between quantity and quality of oocytes retrieved after ovarian stimulation, we compared the protein expression of mouse oocytes and embryos with vs without a background of ovarian stimulation using gonadotropins, administered according to the standard protocol in use since more than 50 years (PMID 13185277; PMID 13475597). The data we gathered contribute to a more complete understanding of embryonic gene expression, by taking into account the effect of the commonly used superovulation.
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Oocyte
SUBMITTER: Hannes Drexler
LAB HEAD: Hannes C. A. Drexler
PROVIDER: PXD026347 | Pride | 2021-12-14
REPOSITORIES: Pride
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