Proteomics analysis LC-MS/MS of human bladder cancer cells

ABSTRACT: A total of 6,526 proteins were identified in this study, of which 5880 proteins contained quantitative information. 1.2 times as the threshold of differential expression change, and statistical test t-test p-value<0.05 as the threshold of significance, among the quantified proteins, the expression of 193 proteins in the T24-KO/T24-V2 comparison group was Up-regulation, and down-regulation of 130 protein expressions (for more information about differences in comparison groups, please see the main body of the report). Based on the above data, we performed systematic bioinformatics analysis (protein function annotation) on all identified proteins based on the above data, and performed all differentially expressed proteins), and performed all differentially expressed proteins), Function classification, function enrichment and cluster analysis based on function enrichment. And combining the above information, it provides a reference direction for in-depth research based on the downstream proteome.

INSTRUMENT(S): Q Exactive Plus, Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Bladder Cell, Cell Culture

DISEASE(S): Urinary Bladder Cancer

SUBMITTER: XiaoLing Ying  

LAB HEAD: XiaoLing Ying

PROVIDER: PXD026559 | Pride | 2022-02-17

REPOSITORIES: Pride