Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Lung, Epithelial Cell Of Lung
DISEASE(S): Non-small Cell Lung Carcinoma
SUBMITTER: Sergio Lilla
LAB HEAD: Sara Rossana Zanivan
PROVIDER: PXD027268 | Pride | 2021-09-28
REPOSITORIES: Pride
Items per page: 1 - 5 of 59 |
Nature communications 20211124 1
Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as cell scattering and invasion. The endosomal system influences how RTK signalling is coded, but the ways in which it transmits these signals to the nucleus to influence gene expression are not yet clear. Here we show that hepatocyte growth factor, an activator of MET (an RTK) ...[more]