Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Ovary
DISEASE(S): Polycystic Ovary Syndrome
SUBMITTER: Tang Ting
LAB HEAD: Bing Yao
PROVIDER: PXD028835 | Pride | 2023-03-11
REPOSITORIES: Pride
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Xue Tongmin T Zhao Shanmeizi S Zhang Hong H Tang Ting T Zheng Lu L Jing Jun J Ge Xie X Ma Rujun R Ma Jinzhao J Ren Xiaoyan X Jueraitetibaike Kadiliya K Guo Zhigang Z Chen Li L Yao Bing B
iScience 20230203 3
Ovarian granulosa cells (GCs) in the follicle are the important mediator of steroidogenesis and foster oocyte maturation. Evidences suggested that the function of GCs could be regulated by <i>S</i>-palmitoylation. However, the role of <i>S</i>-palmitoylation of GCs in ovarian hyperandrogenism remains elusive. Here, we demonstrated that the protein from GCs in ovarian hyperandrogenism phenotype mouse group exhibits lower palmitoylation level compared with that in the control group. Using <i>S</i> ...[more]