Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urinary Bladder
SUBMITTER: Franz Friedrich Dressler
LAB HEAD: Franz Dressler
PROVIDER: PXD029133 | Pride | 2022-05-19
REPOSITORIES: Pride
Action | DRS | |||
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20201106_2020-12_1.1.wiff | Wiff | |||
20201106_2020-12_1.1.wiff.scan | Wiff | |||
20201106_2020-12_2.1.wiff | Wiff | |||
20201106_2020-12_2.1.wiff.scan | Wiff | |||
20201106_2020-12_3.1.wiff | Wiff |
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Clinical proteomics 20220502 1
<h4>Objectives</h4>Formalin-fixed paraffin-embedded (FFPE) tissue is the standard material for diagnostic pathology but poses relevant hurdles to accurate protein extraction due to cross-linking and chemical alterations. While numerous extraction protocols and chemicals have been described, systematic comparative analyses are limited. Various parameters were thus investigated in their qualitative and quantitative effects on protein extraction (PE) efficacy. Special emphasis was put on preservati ...[more]