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Effects of SHetA2 on SiHa and C-33 A human cervical cancer cell lines

ABSTRACT: The objective was to identify how cervical cancer cells respond to treatment with the investigational new agent, Sulfur Heteroartoinoid A2 (SHetA2, NSC 726189) by identify proteins that are detected at significantly different levels in SHetA2-treated compared to untreated control cultures. Triplicate cultures of SiHa and C-33 A human cervical cancer cell lines were treated with 10 micromolar SHetA2 or the same volume of dimethylsulfoxide solvent (untreated controls) for 24 hours. Proteins were extracted from the cultures using M-PER (ThermoFisher).

INSTRUMENT(S): Synapt MS

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Cervix Squamous Epithelium

DISEASE(S): Cervix Carcinoma

SUBMITTER: Virginie Sjoelund

LAB HEAD: Doris M

PROVIDER: PXD029537 | Pride | 2023-08-29

REPOSITORIES: Pride

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			Action	DRS
	181113_RR-4177_1-Siha-CNT-1.mzML	Mzml
	181113_RR-4177_1-Siha-CNT-1.raw.zip	Raw
	181113_RR-4177_1-Siha-CNT-1_IA_final_peptide.csv	Csv
	181113_RR-4177_1-Siha-CNT-1_IA_final_protein.csv	Csv
	181113_RR-4177_2-Siha-ShetA2-1.mzML	Mzml

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