Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Eclipse, Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell
DISEASE(S): Breast Cancer
SUBMITTER: Harmjan Vos
LAB HEAD: Eric Kalkhoven
PROVIDER: PXD030404 | Pride | 2022-02-15
REPOSITORIES: Pride
Items per page: 1 - 5 of 34 |
Cancers 20211216 24
The three human Tribbles (TRIB) pseudokinases have been implicated in a plethora of signaling and metabolic processes linked to cancer initiation and progression and can potentially be used as biomarkers of disease and prognosis. While their modes of action reported so far center around protein-protein interactions, the comprehensive profiling of TRIB interactomes has not been reported yet. Here, we have developed a robust mass spectrometry (MS)-based proteomics approach to characterize Tribbles ...[more]