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Proteomic study of baicalein effects on LPS-primed BV2 microglia

ABSTRACT: To comprehensively study the intracellular signaling changes and explore the underlying mechanisms of baicalein-mediated microglial responses, we employed systemic proteomic approach, using target-free SWATH mass spectra (SWATH-MS), focusing on intracellular proteins. BV2 cells were treated with LPS followed by the addition of vehicle or baicalein and they were cultured for a total of 48 hours before being collected for proteomic analysis.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Microglial Cell Activation

DISEASE(S): Retinal Degeneration

SUBMITTER: Li PAN

LAB HEAD: Chi-Wai Do

PROVIDER: PXD030447 | Pride | 2022-02-14

REPOSITORIES: Pride

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			Action	DRS
	Ctrl_4_swath1.wiff	Wiff
	Ctrl_4_swath1.wiff.scan	Wiff
	Ctrl_5_swath1.wiff	Wiff
	Ctrl_5_swath1.wiff.scan	Wiff
	Ctrl_6_swath1.wiff	Wiff

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