Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human) Toxoplasma Gondii Rh
SUBMITTER: Yohann Couté
LAB HEAD: Yohann Couté
PROVIDER: PXD030932 | Pride | 2022-07-25
REPOSITORIES: Pride
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Nyonda Mary Akinyi MA Boyer Jean-Baptiste JB Belmudes Lucid L Krishnan Aarti A Pino Paco P Couté Yohann Y Brochet Mathieu M Meinnel Thierry T Soldati-Favre Dominique D Giglione Carmela C
Journal of cell science 20220805 15
Acetyl-CoA participates in post-translational modification of proteins and in central carbon and lipid metabolism in several cell compartments. In mammals, acetyl-CoA transporter 1 (AT1, also known as SLC33A1) facilitates the flux of cytosolic acetyl-CoA into the endoplasmic reticulum (ER), enabling the acetylation of proteins of the secretory pathway, in concert with the activity of dedicated acetyltransferases such as NAT8. However, the involvement of the ER acetyl-CoA pool in acetylation of E ...[more]