Proteomics

Dataset Information

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Cross-linking MS of S. cerevisiae ORC bound to DNA and Cdc6


ABSTRACT: During DNA replication initiation, the Origin Recognition Complex (ORC) and Cdc6 co-associate on DNA to load replicative helicases onto origins of replication. We apply DSSO crosslinking mass spectrometry of reconstituted ORC-DNA-Cdc6 to identify interactions between different subunits and domains in the complex.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Jan Seebacher  

LAB HEAD: Franziska Bleichert

PROVIDER: PXD031033 | Pride | 2022-02-28

REPOSITORIES: Pride

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