Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole proteome profiling of WT, N40K insoluble fractions from brain tissues at age of 12 months

ABSTRACT: Analyzing and comparing proteome profiling between WT, N40K-Tg will be beneficial to understand the protein changes in insoluble fractions.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

SUBMITTER: Xian Han

LAB HEAD: Junmin Peng

PROVIDER: PXD031581 | Pride | 2022-08-12

REPOSITORIES: Pride

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	mB05_ins_whp_f01.1.pepXML	Pepxml
	mB05_ins_whp_f01.raw	Raw
	mB05_ins_whp_f02.1.pepXML	Pepxml
	mB05_ins_whp_f02.raw	Raw
	mB05_ins_whp_f03.1.pepXML	Pepxml

Items per page:

1 - 5 of 80

Similar Datasets

Profilling of aggregated proteome in human control and AD cases

Project description:Analyzing and comparing proteome profiling between human control and AD cases will be beneficial to understand the molecular changes of insoluble fractions of AD cases.

2022-08-12 | PXD031587 | Pride

Whole proteome profiling of WT, N40K-Tg, 5xFAD, dTg mice (second batch)

Project description:Analyzing and comparing proteome profiling among WT, N40K-Tg, 5xFAD and dTg will be beneficial to understand the interaction between RNA splicing dysfunction pathway and Amyloid cascade.

2022-08-12 | PXD031545 | Pride

Whole proteome profiling of mouse cultured neurons transduced by N40K lentivirus

Project description:Analyzing and comparing proteome profiling N40K mouse cultured neurons will be beneficial to understand the contributing of RNA splicing dysfunction pathway to Alzheimer's Disease.

2022-08-12 | PXD031546 | Pride

Whole proteome profiling of WT, N40K-Tg, 5xFAD, dTg mice

2022-08-12 | PXD023395 | Pride

Whole proteome and phosphoproteome profiling of CD8+ and CD8- dendritic cells

Project description:Analyzing and comparing proteome and phosphoproteome profiling between CD8+ DC and CD8- DC not only will be very helpful to understand the molecular mechanisms regulating CD8+/- DC differentiation and function but also can screen CD8+ or CD8- DC specific regulatory pathways or molecules.

2018-06-11 | PXD006875 | Pride

Whole proteome and phosphoproteome profiling of APPKI (NL-F) mice

Project description:Analyzing and comparing proteome and phosphoproteome profiling between WT and APPKI (NL-F) KI mice help us understand the molecular changes contributing to amyloid pathology development

2024-10-28 | PXD031734 | Pride

Whole proteome and phosphoproteome profiling of APPKI mice

Project description:Analyzing and comparing proteome and phosphoproteome profiling between WT and APPKI mice help us understand the molecular changes contributing to amyloid pathology development

2024-10-28 | PXD031769 | Pride

Whole proteome and phosphoproteome profiling of APPKI (NL-G-F) mice

Project description:Analyzing and comparing proteome and phosphoproteome profiling between WT and APPKI mice help us understand the molecular changes contributing to amyloid pathology development

2024-10-28 | PXD031735 | Pride

Whole proteome and phosphoproteome profiling of J20 mice

Project description:Analyzing and comparing proteome and phosphoproteome profiling between WT and J20 Tg mice help us understand the molecular changes contributing to amyloid pathology development

2024-10-28 | PXD031732 | Pride

Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy

Project description:Skeletal muscle atrophy is a debilitating condition that occurs with aging and disease but the underlying mechanisms are incompletely understood. Previous work determined that common transcriptional changes occur in muscle during atrophy induced by different stimuli. However, whether this holds true at the proteome level remains largely unexplored. Here, we find that, contrary to this earlier model, distinct atrophic stimuli (corticosteroids, cancer, and aging) induce largely different mRNA and protein changes during muscle atrophy in mice. Moreover, there is widespread transcriptome-proteome disconnect. Consequently, atrophy markers (atrogenes) identified in earlier microarray-based studies do not emerge from these proteomic surveys as the most relevantly associated with atrophy in all conditions. Rather, we identify proteins that are distinctly modulated by different types of atrophy (herein defined as “atroproteins”) such as the myokine CCN1/Cyr61, which regulates myofiber type switching during sarcopenia. Altogether, these integrated analyses indicate that different catabolic stimuli induce muscle atrophy via largely distinct mechanisms.

2022-02-22 | PXD027464 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data