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Multifactorial remodeling of the cancer immunopeptidome by interferon gamma

ABSTRACT: In this study we combined previous transcriptomics and immunopeptidomics data with new proteomics data from untreated and IFNg-treated CRC PDOs to dissect mechanisms that lead to remodeling of the immunopeptidome through IFNg treatment (this is from the paper introduction, let me know if it needs any stylistic changes). · Experiment description: The cells were grown in DMEM/F12 media with 20% fetal bovine serum, 1X Glutamax, 100 units/ml penicillin/streptomycin and 2% matrigel, and treated with 600ng/mL IFNg for 48 hours before harvesting. Cells were washed twice with ice-cold PBS then snap-frozen.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: James Wright

LAB HEAD: Jyoti Choudhary

PROVIDER: PXD031634 | Pride | 2023-09-29

REPOSITORIES: Pride

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			Action	DRS
	AN02B_TMT8plex.pdStudy	Other
	AN02B_TMT8plex_All28.msf	Msf
	AN02B_TMT8plex_All28.pdResult	Other
	AN02B_TMT8plex_All28_Proteins.xlsx	Xlsx
	Lumos1_AN02B_TMT8plex_P01.raw	Raw

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