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LC-MS/MS of human MFN2 interaction proteins

ABSTRACT: LC-MS/MS of human MFN2 interaction proteins from 293T cells or 786-O cells

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Kidney Cell

DISEASE(S): Kidney Cancer

SUBMITTER: Gao Song

LAB HEAD: Gao Song

PROVIDER: PXD033112 | Pride | 2023-10-24

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20201112-YJF-786-0.mgf	Mgf
	20201112YJF-293T.mgf	Mgf
	293T.raw	Raw
	2_peptides_1_1_0.mzid.gz	Mzid
	786-0.raw	Raw

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1 - 5 of 7

Publications

MFN2 suppresses clear cell renal cell carcinoma progression by modulating mitochondria-dependent dephosphorylation of EGFR.

Luo Li L Wei Denghui D Pan Yihui Y Wang Qiu-Xia QX Feng Jian-Xiong JX Yu Bing B Kang Tiebang T Luo Junhang J Yang Jiefeng J Gao Song S

Cancer communications (London, England) 20230628 7

<h4>Background</h4>Clear cell renal cell carcinoma (ccRCC) is the most lethal renal cancer. An overwhelming increase of patients experience tumor progression and unfavorable prognosis. However, the molecular events underlying ccRCC tumorigenesis and metastasis remain unclear. Therefore, uncovering the underlying mechanisms will pave the way for developing novel therapeutic targets for ccRCC. In this study, we sought to investigate the role of mitofusin-2 (MFN2) in supressing ccRCC tumorigenesis ...[more]

PMID: 37378422

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