Proteomics

Dataset Information

0

Proteomic analysis of Blastocrithidia nonstop


ABSTRACT: Proteomic analysis was performed to confirm the identity of in-frame stop codons

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Blastocrithidia Sp. P57

SUBMITTER: David Potesil  

LAB HEAD: Zbynek Zdrahal

PROVIDER: PXD033324 | Pride | 2022-12-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Blastocrithidia_nonstop.mgf Mgf
Blastocrithidia_nonstop.msf Msf
Blastocrithidia_nonstop.pep.xml Pepxml
Blastocrithidia_nonstop.prot.xml Xml
Blastocrithidia_nonstop.raw Raw
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Publications


Cognate tRNAs deliver specific amino acids to translating ribosomes according to the standard genetic code, and three codons with no cognate tRNAs serve as stop codons. Some protists have reassigned all stop codons as sense codons, neglecting this fundamental principle<sup>1-4</sup>. Here we analyse the in-frame stop codons in 7,259 predicted protein-coding genes of a previously undescribed trypanosomatid, Blastocrithidia nonstop. We reveal that in this species in-frame stop codons are underrepr  ...[more]

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