Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Blastocrithidia Sp. P57
SUBMITTER: David Potesil
LAB HEAD: Zbynek Zdrahal
PROVIDER: PXD033324 | Pride | 2022-12-12
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Blastocrithidia_nonstop.mgf | Mgf | |||
Blastocrithidia_nonstop.msf | Msf | |||
Blastocrithidia_nonstop.pep.xml | Pepxml | |||
Blastocrithidia_nonstop.prot.xml | Xml | |||
Blastocrithidia_nonstop.raw | Raw |
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Kachale Ambar A Pavlíková Zuzana Z Nenarokova Anna A Roithová Adriana A Durante Ignacio M IM Miletínová Petra P Záhonová Kristína K Nenarokov Serafim S Votýpka Jan J Horáková Eva E Ross Robert L RL Yurchenko Vyacheslav V Beznosková Petra P Paris Zdeněk Z Valášek Leoš Shivaya LS Lukeš Julius J
Nature 20230111 7945
Cognate tRNAs deliver specific amino acids to translating ribosomes according to the standard genetic code, and three codons with no cognate tRNAs serve as stop codons. Some protists have reassigned all stop codons as sense codons, neglecting this fundamental principle<sup>1-4</sup>. Here we analyse the in-frame stop codons in 7,259 predicted protein-coding genes of a previously undescribed trypanosomatid, Blastocrithidia nonstop. We reveal that in this species in-frame stop codons are underrepr ...[more]