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Effect of chinese madicine on plasma exosomal proteins in Primary Sjogren's syndrome

ABSTRACT: Modified Zengye Decoction, a traditional chinese medicine, can effectively alleviate SS symptoms, while its mechanism may be associated with the reduced protein expression in insulin response, porphyrin and chlorophyll metabolism, and the TLR4/NF-κB pathway.

INSTRUMENT(S): 6410 Triple Quadrupole LC/MS

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Sjogren's Syndrome

SUBMITTER: peng yang

LAB HEAD: Peng Yang

PROVIDER: PXD033627 | Pride | 2022-10-15

REPOSITORIES: Pride

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			Action	DRS
	Search_results.zip	Other
	T480_LFQ_WKB002_Post_SS1.raw	Raw
	T480_LFQ_WKB002_Post_SS2.raw	Raw
	T480_LFQ_WKB002_Post_SS3.raw	Raw
	T480_LFQ_WKB002_Pre_SS1.raw	Raw

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Publications

Therapeutic effect of modified zengye decoction on primary Sjogren's syndrome and its effect on plasma exosomal proteins.

Zeng Yimin Y Peng Xin X Wang Yun Y Hou Lei L Ma Wukai W Yang Peng P

Frontiers in pharmacology 20220826

Background: Modified Zengye Decoction (MZD), a traditional Chinese medicine, is an effective treatment for patients with primary Sjögren's syndrome (pSS). Purpose: To evaluate the efficacy of MZD and investigate its effect on plasma exosomal proteins. Methods: Eighteen pSS patients were treated with MZD for 2 weeks. The therapeutic effect was evaluated by observing the changes in clinical symptoms, laboratory parameters, and plasma cytokines before and after treatment ...[more]

PMID: 36091838

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