Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Pseudomonas Aeruginosa
SUBMITTER: Evelin Berger
LAB HEAD: Carina Sihlbom
PROVIDER: PXD033690 | Pride | 2023-07-20
REPOSITORIES: Pride
Action | DRS | |||
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MaxQuant_rawdata_PA_OMVs_and_aOMVs.xlsx | Xlsx | |||
QEHF_181015_06.raw | Raw | |||
QEHF_181015_09.raw | Raw | |||
QEHF_181015_12.raw | Raw | |||
QEHF_181015_15.raw | Raw |
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Journal of nanobiotechnology 20230519 1
The development of vaccines based on outer membrane vesicles (OMV) that naturally bud off from bacteria is an evolving field in infectious diseases. However, the inherent inflammatory nature of OMV limits their use as human vaccines. This study employed an engineered vesicle technology to develop synthetic bacterial vesicles (SyBV) that activate the immune system without the severe immunotoxicity of OMV. SyBV were generated from bacterial membranes through treatment with detergent and ionic stre ...[more]