Proteomics

Dataset Information

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Sperm motility annotated genes: are they associated with impaired fecundity?


ABSTRACT: To determine whether Gene Ontology sperm motility annotated genes are differentially abundant in sperm collected from men with oligoasthenozoospermia and to gain further insight into molecular mechanisms underlying male infertility

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Spermatocyte

SUBMITTER: Markus Räschle  

LAB HEAD: Markus Räschle

PROVIDER: PXD033749 | Pride | 2023-07-20

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20210928_HF1_MaRa_SA_P0133_S10.raw Raw
20210928_HF1_MaRa_SA_P0133_S11.raw Raw
20210928_HF1_MaRa_SA_P0133_S12.raw Raw
20210928_HF1_MaRa_SA_P0133_S13_02.raw Raw
20210928_HF1_MaRa_SA_P0133_S2.raw Raw
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Publications

Sperm Motility Annotated Genes: Are They Associated with Impaired Fecundity?

Abu-Halima Masood M   Becker Lea Simone LS   Al Smadi Mohammad A MA   Abdul-Khaliq Hashim H   Raeschle Markus M   Meese Eckart E  

Cells 20230425 9


Sperm motility is a prerequisite for achieving pregnancy, and alterations in sperm motility, along with sperm count and morphology, are commonly observed in subfertile men. The aim of the study was to determine whether the expression level of genes annotated with the Gene Ontology (GO) term 'sperm motility' differed in sperm collected from healthy men and men diagnosed with oligoasthenozoospermia. Reverse transcription quantitative real-time PCR (RT-qPCR), quantitative mass spectrometry (LC-MS/M  ...[more]

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