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Mesenchymal stem cells-derived exosomes and MRC-5 cell-derived exosomes LC-MSMS

ABSTRACT: We compared the differential proteins between Mesenchymal stem cells-derived exosomes MRC-5 cell-derived exosomes.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Peipei Liu

LAB HEAD: Huaping Daic

PROVIDER: PXD033839 | Pride | 2024-05-21

REPOSITORIES: Pride

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			Action	DRS
	MRC-5-Exo-1.raw	Raw
	MRC-5-Exo-2.raw	Raw
	MRC-5-Exo-3.raw	Raw
	MSCs-Exo-1.raw	Raw
	MSCs-Exo-2.raw	Raw

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Publications

Mesenchymal Stem Cells-Derived Exosomes Alleviate Acute Lung Injury by Inhibiting Alveolar Macrophage Pyroptosis.

Liu Peipei P Yang Shengnan S Shao Xuecheng X Li Chen C Wang Zai Z Dai Huaping H Wang Chen C

Stem cells translational medicine 20240401 4

Acute lung injury (ALI) is an important pathological process of acute respiratory distress syndrome, yet there are limited therapies for its treatment. Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been shown to be effective in suppressing inflammation. However, the effects of MSCs-Exo on ALI and the underlying mechanisms have not been well elucidated. Our data showed that MSCs-Exo, but not exosomes derived from MRC-5 cells (MRC-5-Exo), which are human fetal lung fibroblast cells, sign ...[more]

PMID: 38349749

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