Dataset Information
Global proteome comparison between MEF cells and mESC-R1 cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture
SUBMITTER: 
Fangyuan Cheng
LAB HEAD: Mian Wu
PROVIDER: PXD034181 | Pride | 2023-03-10
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Search_result.zip | Other | |||
| Z9100LQ_MEF_1.raw | Raw | |||
| Z9100LQ_MEF_2.raw | Raw | |||
| Z9100LQ_MEF_3.raw | Raw | |||
| Z9100LQ_MEF_4.raw | Raw |
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Publications
P21-Activated Kinase 4 Pak4 Maintains Embryonic Stem Cell Pluripotency via Akt Activation.
Stem cells (Dayton, Ohio) 20221001 10
Exploiting the pluripotent properties of embryonic stem cells (ESCs) holds great promise for regenerative medicine. Nevertheless, directing ESC differentiation into specialized cell lineages requires intricate control governed by both intrinsic and extrinsic factors along with the actions of specific signaling networks. Here, we reveal the involvement of the p21-activated kinase 4 (Pak4), a serine/threonine kinase, in sustaining murine ESC (mESC) pluripotency. Pak4 is highly expressed in R1 ESC ...[more]
