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Proteomics on Nav1.8-positive nociceptors of mouse DRG

ABSTRACT: Nociceptors play an essential role in both acute pain and chronic pain conditions. In this study, we examined the proteome of mouse dorsal root ganglia and compared NaV1.8Cre+/-; ROSA26-flox-stop-flox-DTA (Diphtheria toxin fragment A) mutant mice (NaV1.8Cre-DTA), in which NaV1.8-positive neurons (mainly nociceptors) in dorsal root ganglia (DRG) were ablated, with respective littermate wildtype controls.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Dorsal Root Ganglion

SUBMITTER: Manuela Schmidt

LAB HEAD: Univ.-Prof. Manuela Schmidt, PhD

PROVIDER: PXD034447 | Pride | 2022-10-03

REPOSITORIES: Pride

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			Action	DRS
	20190227_122917_Woods_samples_DirectDIAAnalysi_...__.sne	Other
	20190227_122945_Woods_samples_SpecLibDIAAnalys_...__.sne	Other
	D_D181213_S2215-S1-wt_MHRM_R01_T0.raw	Raw
	D_D181213_S2215-S2-wt_MHRM_R01_T0.raw	Raw
	D_D181213_S2215-S3-wt_MHRM_R01_T0.raw	Raw

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