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Graft versus host disease treatment with mesenchymal stem cells

ABSTRACT: graft versus host disease organoids were co-cultured with mesenchymal stem cells

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Stem Cell, Cell Culture

DISEASE(S): Disease Free

SUBMITTER: Suzy Varderidou

LAB HEAD: Suzy varderidou-minasian, Magdalena Lorenowicz, Maarten Altelaar, Bahar Arik

PROVIDER: PXD034822 | Pride | 2024-05-22

REPOSITORIES: Pride

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			Action	DRS
	20211010_EX2_UM1_Damen101_SA_EXT02_BU_10000_MSC_donr_17.xlsx	Xlsx
	20211010_EX2_UM1_Damen101_SA_EXT02_BU_10000_MSC_donr_5.xlsx	Xlsx
	20211010_EX2_UM1_Damen101_SA_EXT02_BU_10000_MSC_donr_8.xlsx	Xlsx
	20211010_EX2_UM1_Damen101_SA_EXT02_BU_no_MSC_donr_17.xlsx	Xlsx
	20211010_EX2_UM1_Damen101_SA_EXT02_BU_no_MSC_donr_5.xlsx	Xlsx

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Publications

Mesenchymal stromal/stem cells promote intestinal epithelium regeneration after chemotherapy-induced damage.

Yetkin-Arik B B Jansen S A SA Varderidou-Minasian S S Westendorp B B Skarp K-P KP Altelaar M M Lindemans C A CA Lorenowicz M J MJ

Stem cell research & therapy 20240429 1

<h4>Background</h4>Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for leukemia and a range of non-malignant disorders. The success of the therapy is hampered by occurrence of acute graft-versus-host disease (aGvHD); an inflammatory response damaging recipient organs, with gut, liver, and skin being the most susceptible. Intestinal GvHD injury is often a life-threatening complication in patients unresponsive to steroid treatment. Allogeneic mesenchymal stromal/s ...[more]

PMID: 38679715

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