Proteomics

Dataset Information

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Proteomics analysis of cerebrospinal fluid (CSF) from multiple sclerosis patients


ABSTRACT: Innovative pro-regenerative treatment strategies for progressive multiple sclerosis (PMS), combining neuroprotection and immunomodulation, represents an unmet need. Neural precursor cells (NPCs) transplanted in animal models of multiple sclerosis promote neuroprotection and remyelination by releasing molecules sustaining trophic support and neural plasticity. We present the results of STEMS, a single dose escalation phase I clinical trial, evaluating the feasibility, safety, and tolerability of intrathecally transplanted human fetal NPCs (hfNPCs) in 12 PMS patients.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cerebrospinal Fluid

DISEASE(S): Multiple Sclerosis

SUBMITTER: Annapaola Andolfo  

LAB HEAD: Gianvito Martino

PROVIDER: PXD034840 | Pride | 2022-11-18

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
F006350.mzid.gz Mzid
F006351.mzid.gz Mzid
F006352.mzid.gz Mzid
F006379.mzid.gz Mzid
F006380.mzid.gz Mzid
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