Proteomics

Dataset Information

0

Parallel comparison of mutant proteomes with altered carbon metabolism reveals Hik8 regulates PII phosphorylation and the basal level glycogen accumulation in a cyanobacterium


ABSTRACT: To understand the specificity and the cross-talk of such regulations, we simultaneously and quantitatively compared the proteomes of the gene knockout mutants for the regulators. A number of proteins showing differential expression in one or more mutants were identified, including four proteins that are unanimously upregulated or downregulated in all the five mutants. These represent the important nodes of the intricate and elegant regulatory network for carbon metabolism.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Synechocystis Sp. Pcc 6803

SUBMITTER: Chengcheng Huang  

LAB HEAD: Yingchun Wang

PROVIDER: PXD035864 | Pride | 2023-07-20

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
HCC_TMT_1_F10_20180514.raw Raw
HCC_TMT_1_F11_20180514.raw Raw
HCC_TMT_1_F12_20180514.raw Raw
HCC_TMT_1_F13_20180514.raw Raw
HCC_TMT_1_F14_20180514.raw Raw
Items per page:
1 - 5 of 44
altmetric image

Publications

Parallel Proteomic Comparison of Mutants With Altered Carbon Metabolism Reveals Hik8 Regulation of P<sub>II</sub> Phosphorylation and Glycogen Accumulation in a Cyanobacterium.

Huang Chengcheng C   Duan Xiaoxiao X   Ge Haitao H   Xiao Zhen Z   Zheng Limin L   Wang Gaojie G   Dong Jinghui J   Wang Yan Y   Zhang Yuanya Y   Huang Xiahe X   An Hongyu H   Xu Wu W   Wang Yingchun Y  

Molecular & cellular proteomics : MCP 20230522 7


Carbon metabolism is central to photosynthetic organisms and involves the coordinated operation and regulation of numerous proteins. In cyanobacteria, proteins involved in carbon metabolism are regulated by multiple regulators including the RNA polymerase sigma factor SigE, the histidine kinases Hik8, Hik31 and its plasmid-borne paralog Slr6041, and the response regulator Rre37. To understand the specificity and the cross-talk of such regulations, we simultaneously and quantitatively compared th  ...[more]

Similar Datasets

2023-07-20 | PXD035898 | Pride
2023-02-17 | PXD036113 | Pride
2021-11-10 | PXD023181 | Pride
2023-03-20 | PXD035771 | Pride
2015-01-16 | PXD001246 | Pride
2016-05-09 | PXD001831 | Pride
2019-07-10 | PXD013411 | Pride
2023-01-04 | PXD035632 | Pride
2017-05-19 | PXD005085 | Pride
2024-01-05 | PXD033243 | Pride