Proteomics

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Homologous genes shared between probiotics and pathogens affected the adhesion of probiotics and exclusion of pathogens in gut mucus


ABSTRACT: Clarifying mechanisms underlying the selective adhesion of probiotics and competitive exclusion of pathogens in the intestine is a central theme of maintaining host health.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Lactiplantibacillus Pentosus

TISSUE(S): Cell Culture

SUBMITTER: Yujie Sha  

LAB HEAD: Yujie Sha

PROVIDER: PXD036035 | Pride | 2023-07-20

REPOSITORIES: Pride

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HFX4_FPEP210030998-1A.raw Raw
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Publications

Homologous genes shared between probiotics and pathogens affect the adhesion of probiotics and exclusion of pathogens in the gut mucus of shrimp.

Sha Yujie Y   Yan Qingyun Q   Liu Jian J   Yu Jiafeng J   Xu Shicai S   He Zhili Z   Ren Jing J   Qu Jie J   Zheng Shiying S   Wang Guomin G   Dong Weiying W  

Frontiers in microbiology 20230614


Clarifying mechanisms underlying the selective adhesion of probiotics and competitive exclusion of pathogens in the intestine is a central theme for shrimp health. Under experimental manipulation of probiotic strain (i.e., <i>Lactiplantibacillus plantarum</i> HC-2) adhesion to the shrimp mucus, this study tested the core hypothesis that homologous genes shared between probiotic and pathogen would affect the adhesion of probiotics and exclusion of pathogens by regulating the membrane proteins of  ...[more]

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