Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Suspension Culture, Glioblastoma Multiforme Cancer Stem Cell
DISEASE(S): Glioblastoma
SUBMITTER: Tolga Lokumcu
LAB HEAD: Dr. Violaine Goidts
PROVIDER: PXD036359 | Pride | 2024-05-21
REPOSITORIES: Pride
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UP000005640_9606.fasta | Fasta | |||
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oecf3-TL0406-02.raw | Raw | |||
oecf3-TL0406-03.raw | Raw | |||
oecf3-TL0406-04.raw | Raw |
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ACS nano 20240111 3
Glioblastoma is a deadly brain tumor for which there is no cure. The presence of glioblastoma stem-like cells (GSCs) contributes to the heterogeneous nature of the disease and makes developing effective therapies challenging. Glioblastoma cells have been shown to influence their environment by releasing biological nanostructures known as extracellular vesicles (EVs). Here, we investigated the role of GSC-derived nanosized EVs (<200 nm) in glioblastoma heterogeneity, plasticity, and aggressivenes ...[more]