Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: shuang Zhao
LAB HEAD: zhao shuang
PROVIDER: PXD036634 | Pride | 2024-07-03
REPOSITORIES: Pride
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Zhao Shuang S Li Jie J Duan Songqi S Liu Chang C Wang Hua H Lu Jiangtao J Zhao Nannan N Sheng Xiaoyan X Wu Yiwei Y Li Yanjun Y Sun Baofa B Liu Lin L
Stem cell research & therapy 20240621 1
<h4>Background</h4>Telomeres consist of repetitive DNA sequences at the chromosome ends to protect chromosomal stability, and primarily maintained by telomerase or occasionally by alternative telomere lengthening of telomeres (ALT) through recombination-based mechanisms. Additional mechanisms that may regulate telomere maintenance remain to be explored. Simultaneous measurement of telomere length and transcriptome in the same human embryonic stem cell (hESC) revealed that mRNA expression levels ...[more]