Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Danio Rerio (zebrafish) (brachydanio Rerio)
TISSUE(S): Embryo
SUBMITTER: Steve Ayobahan
LAB HEAD: Dr. Sebastian Eilebrecht
PROVIDER: PXD036875 | Pride | 2023-02-25
REPOSITORIES: Pride
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Ayobahan Steve U SU Alvincz Julia J Reinwald Hannes H Strompen Jannis J Salinas Gabriela G Schäfers Christoph C Eilebrecht Elke E Eilebrecht Sebastian S
Ecotoxicology and environmental safety 20230104
Endocrine disruptors (EDs), capable of modulating the sex hormone system of an organism, can exert long-lasting negative effects on reproduction in both humans and the environment. For these reasons, the properties of EDs prevent a substance from being approved for marketing. However, regulatory testing to evaluate endocrine disruption is time-consuming, costly, and animal-intensive. Here, we combined sublethal zebrafish embryo assays with transcriptomics and proteomics for well-characterized en ...[more]