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Alpha4 is critical for Adipocyte Maintenance and Mitochondrial Homeostasis through Regulation of Insulin Signaling

ABSTRACT: To investigate how α4 (IGBP1) regulates insulin signaling in adipocytes, we conducted analysis of proteins that interact with α4 by using brown preadipocyte cell lines (WT-1 cells) transfected with 3XFlag-tagged α4 protein, followed by immunoprecipitation of associated proteins using anti-Flag beads and mass spectroscopic proteomic analysis.

INSTRUMENT(S): Thermo Fisher Scientific instrument model

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Preadipocyte, Brown Preadipocyte

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: Yuma Okubo

LAB HEAD: masaji sakaguchi

PROVIDER: PXD036915 | Pride | 2022-10-17

REPOSITORIES: pride

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			Action	DRS
	KK0675-1_Control.mzML	Mzml
	KK0675-1_Control.raw	Raw
	KK0675-2_Flag-IGBP1_1.mzML	Mzml
	KK0675-2_Flag-IGBP1_1.raw	Raw
	KK0675-3_Flag-IGBP1_2.mzML	Mzml

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