Novel compounds modulating Mycobacterium marinum ESX-5 secretion display anti-mycobacterial activity in vivo
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ABSTRACT: We observed through Western blot that Mycobacterium marinum secreted more highly abundant PE-PGRS proteins that are above 130 kDa when treated with compound 36 than mock-treated bacteria. We would like to explore which PE-PGRS proteins are more secreted in this condition and whether other proteins are also differentially secreted between two conditions.
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Mycobacterium Marinum Atcc Baa-535 Bacteria
DISEASE(S): Tuberculosis
SUBMITTER: Sander Piersma
LAB HEAD: Connie Jimenez
PROVIDER: PXD037981 | Pride | 2023-01-19
REPOSITORIES: Pride
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