Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Danio Rerio (zebrafish) (brachydanio Rerio)
TISSUE(S): Embryo
SUBMITTER: Virginie Salnot
LAB HEAD: Eric Battaglia
PROVIDER: PXD038229 | Pride | 2023-03-11
REPOSITORIES: pride
Items per page: 1 - 5 of 52 |
International journal of molecular sciences 20221216 24
Despite the involvement of several serine hydrolases (SHs) in the metabolism of xenobiotics such as dibutyl phthalate (DBP), no study has focused on mapping this enzyme class in zebrafish, a model organism frequently used in ecotoxicology. Here, we survey and identify active SHs in zebrafish larvae and search for biological markers of SH type after exposure to DBP. Zebrafish were exposed to 0, 5, and 100 µg/L DBP from 4 to 120 h post-fertilization. A significant decrease in vitellogenin expressi ...[more]