Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Superior Mesenteric Artery
DISEASE(S): Aortic Aneurysm
SUBMITTER: Brian Hampton
LAB HEAD: Dudley Strickland
PROVIDER: PXD038236 | Pride | 2023-03-11
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
2022-03-08-decoys-contam-UP000000589_10090.fasta.fas | Fasta | |||
checksum.txt | Txt | |||
combined_modified_peptide.tsv | Tabular | |||
combined_peptide.tsv | Tabular | |||
combined_protein.tsv | Tabular |
Items per page: 1 - 5 of 34 |
JCI insight 20230124 2
Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor-related protein 1 (LRP1), a large endocytic signaling receptor that recognizes numerous ligands, including apolipoprotein E-rich lipoproteins, proteases, and protease-inhibitor complexes. We observed the spontaneous formation of aneurysms in the superior mesenteric artery (SMA) of both male and female mice in which LRP1 was ...[more]