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Identification of cell surface proteins in Zdhhc20 KO cells

ABSTRACT: An shRNA screen to search for the mediators of pancreatic cancer metastasis identified palmitoyl transferase ZDHHC20 as a protein that mediates this process by promoting the outgrowth of metastatic cells in vivo, We generated a KO of Zdhhc20 using Cas9/CRISPR and sought to determine the changes in the cell surface proteome in KO cells versus parental cells.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Pancreatic Duct

DISEASE(S): Pancreatic Cancer

SUBMITTER: Goran Tomic

LAB HEAD: Julian Downward

PROVIDER: PXD038384 | Pride | 2023-02-09

REPOSITORIES: Pride

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			Action	DRS
	20210420_BR2183_E4_R1.raw	Raw
	20210420_BR2183_E4_R2.raw	Raw
	20210420_BR2183_E4_R3.raw	Raw
	20210420_BR2183_PAR_R1.raw	Raw
	20210420_BR2183_PAR_R2.raw	Raw

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Project description:Identification of the Zdhhc20 KO transcriptome

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