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ProSight Native Complex Down Analysis of Aquaporin Z

ABSTRACT: In this dataset, we analyzed Aquaporin Z using native mass spectrometry. The data was then input into ProSight Native to determine the protein complex composition.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Escherichia Coli

SUBMITTER: Kenneth Durbin

LAB HEAD: Kenneth Durbin

PROVIDER: PXD038817 | Pride | 2023-08-14

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	2022-07-05_AQPZ_IST200_12kres_avg100.RAW	Raw
	2022-07-05_AQPZ_IST250_12kres_avg100.RAW	Raw
	2022-07-05_AQPZ_IST300_12kres_avg100.RAW	Raw
	2022-07-05_AQPZ_iso6184_HCD300_avg999.RAW	Raw
	AqpZ_6184.pcml	Other

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Publications

ProSight Native: Defining Protein Complex Composition from Native Top-Down Mass Spectrometry Data.

Durbin Kenneth R KR Robey Matthew T MT Voong Lilien N LN Fellers Ryan T RT Lutomski Corinne A CA El-Baba Tarick J TJ Robinson Carol V CV Kelleher Neil L NL

Journal of proteome research 20230712 8

Native mass spectrometry has recently moved alongside traditional structural biology techniques in its ability to provide clear insights into the composition of protein complexes. However, to date, limited software tools are available for the comprehensive analysis of native mass spectrometry data on protein complexes, particularly for experiments aimed at elucidating the composition of an intact protein complex. Here, we introduce ProSight Native as a start-to-finish informatics platform for an ...[more]

PMID: 37436406

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