Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Ana Martinez-Val
LAB HEAD: Jesper Velgaard Olsen
PROVIDER: PXD038947 | Pride | 2023-05-18
REPOSITORIES: Pride
Items per page: 1 - 5 of 333 |
Nature communications 20230616 1
Achieving sufficient coverage of regulatory phosphorylation sites by mass spectrometry (MS)-based phosphoproteomics for signaling pathway reconstitution is challenging, especially when analyzing tiny sample amounts. To address this, we present a hybrid data-independent acquisition (DIA) strategy (hybrid-DIA) that combines targeted and discovery proteomics through an Application Programming Interface (API) to dynamically intercalate DIA scans with accurate triggering of multiplexed tandem mass sp ...[more]