Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Clostridioides Difficile Atcc 43255
SUBMITTER: Megan Matthews
LAB HEAD: Megan L. Matthews
PROVIDER: PXD039143 | Pride | 2023-03-11
REPOSITORIES: Pride
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20210113_KBVI128_1.raw | Raw |
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Frontiers in pharmacology 20230126
Many enzymes require post-translational modifications or cofactor machinery for primary function. As these catalytically essential moieties are highly regulated, they act as dual sensors and chemical handles for context-dependent metabolic activity. <i>Clostridioides difficile</i> is a major nosocomial pathogen that infects the colon. Energy generating metabolism, particularly through amino acid Stickland fermentation, is central to colonization and persistence of this pathogen during infection. ...[more]